KMID : 0363320200410010081
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Journal of Korean Oriental Internal Medicine 2020 Volume.41 No. 1 p.81 ~ p.87
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A Case Report of FOLFOX-induced Adverse Events in a Patient with Recurrent Advanced Gastric Cancer Treated with Korean Medicine
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Ko Myung-Hyun
Yang Jae-Ho Jeon Hyung-Joon Cho Chong-Kwan Lee Yeon-Weol Park So-Jung Yoo Hwa-Seung
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Abstract
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Objective: The purpose of this study was to report the clinical effectiveness of Korean medicine treatment on FOLFOX-induced symptoms such as nausea and dizziness in a patient with recurrent advanced gastric adenocarcinoma.
Methods: The patient was diagnosed with recurrent advanced gastric cancer and had FOLFOX-induced nausea and dizziness. The patient was treated with Samchulgunbi-tang and Banhasashim-tang for symptom management. The clinical outcomes were measured by National Cancer Institute Common Terminology Criteria for Adverse Event (NCI CTCAE) and a numeral rating scale (NRS).
Results: After treatment, the patient's nausea and dizziness were relieved from NRS 9 to 2 and NRS 8 to 2 respectively. During and after treatment, no severe toxicities were detected on laboratory findings.
Conclusion: This case study suggests that Samchulgunbi-tang and Banhasashim-tang may relieve symptoms of FOLFOX-induced nausea and dizziness.
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KEYWORD
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advanced gastric cancer, adenocarcinoma, Korean medicine, quality of life, nausea, dizziness
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